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This occurs when a muscle's motor unit is stimulated by multiple impulses at a sufficiently high frequency. Each stimulus causes a twitch. If stimuli are delivered slowly enough, the tension in the muscle will relax between successive twitches. If stimuli are delivered at high frequency, the twitches will overlap, resulting in tetanic contraction.
Generally, this allows a 2 to 4-fold change in force. In general, the motor unit firing rate of each individual motor unit increases with increasing muscular effort until a maximum rate is reached. This smooths out the incremental force changes which would otherwise occur as each additional unit was recruited. [17]
Low doses are insufficient to generate a response, while high doses generate a maximal response. The steepest point of the curve corresponds with an EC 50 of 0.7 molar The dose–response relationship , or exposure–response relationship , describes the magnitude of the response of an organism , as a function of exposure (or doses ) to a ...
In physiology, the all-or-none law (sometimes the all-or-none principle or all-or-nothing law) is the principle that if a single nerve fibre is stimulated, it will always give a maximal response and produce an electrical impulse of a single amplitude. If the intensity or duration of the stimulus is increased, the height of the impulse will ...
As the stimulus increases, the amplitude of the F-wave increases only slightly, and the H-wave decreases, and at supramaximal stimulus, the H-wave will disappear. The M-wave does the opposite of the H-wave. As the stimulus increases the M-wave increases. There is a point of minimal stimulus where the M-wave is absent and the H-wave is maximal.
The stimulus–response model is a conceptual framework in psychology that describes how individuals react to external stimuli.According to this model, an external stimulus triggers a reaction in an organism, often without the need for conscious thought.
Threshold tracking allows for the strength of a test stimulus to be adjusted by a computer in order to activate a defined fraction of the maximal nerve or muscle potential. A threshold tracking experiment consists of a 1-ms stimulus being applied to a nerve in regular intervals. [10]
In neurobiology, a tetanic stimulation consists of a high-frequency sequence of individual stimulations of a neuron. [citation needed] It is associated with potentiation. ...