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Usual Adult Dose for Urinary Alkalinization. Parenteral: 50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour. Oral: 325 to 2000 mg orally 1 to 4 times a day. One gram provides 11.9 mEq (mmoL) each of sodium and bicarbonate. The goal of therapy is to correct serum pH and increase the ...
Lithium Dosage and Administration. Recommended starting dosage for adults and pediatric patients over 30 kg (2.2): Tablets: 300 mg, three times daily. Recommended starting dosage for pediatric patients 20 to 30 kg (2.2): Tablets: 300 mg twice daily. Obtain serum lithium concentration assay after 3 days, drawn 12 hours after the last oral dose ...
Avoid Potassium Chloride in Sodium Chloride Injection, USP in patients with, or at risk for, hypernatremia or hyperchloremia. If use cannot be avoided, monitor serum sodium and chloride concentrations and acid-base balance. Rapid correction of hypernatremia is potentially dangerous with risk of serious neurologic complications.
Hyponatremia refers to a low concentration of sodium in the blood and occurs when athletes sweat profusely and then drink copious amounts of pure water to replenish fluids, without adequately replacing electrolytes. It occurs more frequently during endurance events that last longer than several hours, where athletes attempting to rehydrate over ...
Phenytoin Sodium Description. Phenytoin Sodium Injection, USP is a sterile solution of 50 mg phenytoin sodium per milliliter for intravenous or intramuscular administration. The solution is in a vehicle containing 40% propylene glycol and 10% alcohol in water for injection, adjusted to pH 12 with sodium hydroxide.
Gentamicin Sodium Chloride - Clinical Pharmacology. After intramuscular (IM) administration of gentamicin sulfate, peak serum concentrations usually occur between 30 to 60 minutes and serum levels are measurable for 6 to 8 hours.
Maximum dose: 60 mg/kg/day. Initial Therapy: 15 mg/kg/day orally (see below for frequency) Maximum Recommended Dose: 60 mg/kg/day. CONVERSION From Delayed-Release to Extended-Release: Patients should receive an extended-release dose that is 8% to 20% higher than the total daily dose of the delayed-release.
Dextrose injected parenterally undergoes oxidation to carbon dioxide and water. Sodium chloride in water dissociates to provide sodium (Na +) and chloride (Cl¯) ions. Sodium (Na +) is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Chloride (Cl¯) has an integral role ...
Phenytoin formulations containing the free acid form of the drug (oral suspension and chewable tablets) have approximately 8% greater drug content than phenytoin sodium formulations (extended-release capsules and injection); consider the difference when switching from the free acid to sodium salt form or vice versa.
Ensure serum sodium level is within normal range prior to initiating sodium thiosulfate. Administer sodium thiosulfate as an IV infusion over 15 minutes starting 6 hours after completion of a cisplatin infusion. For multiday cisplatin regimens, administer sodium thiosulfate 6 hours after each cisplatin infusion and at least 10 hours before the ...