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13.4 Over-the-counter. 14 Adjunctive treatments. ... This is a complete list of clinically approved prescription antidepressants throughout the world, ...
An antidepressant may show statistical efficacy even when thoughts of suicide increase but sleep is improved, or for that matter, an antidepressant that as a side effect increase sexual and gastrointestinal symptom ratings may register as being less effective in treating the depression itself than it actually is. [9]
Some people may need antidepressants for a relatively short period (like while grieving the loss of a loved one), or they might need medication long-term, if the depression is chronic.
Some depression rating scales are completed by patients. The Beck Depression Inventory, for example, is a 21-question self-report inventory that covers symptoms such as irritability, fatigue, weight loss, lack of interest in sex, and feelings of guilt, hopelessness or fear of being punished. [11]
Research regarding the effectiveness of antidepressants for depression in adults is controversial and has found both benefits [14] and drawbacks. [15] Meanwhile, evidence of benefit in children and adolescents is unclear, [16] [17] even though antidepressant use has considerably increased in children and adolescents in the 2000s. [18]
In general, sertraline efficacy is similar to that of other antidepressants. [32] For example, a meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with depression. [33]
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