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A palindromic sequence is a nucleic acid sequence in a double-stranded DNA or RNA molecule whereby reading in a certain direction (e.g. 5' to 3') on one strand is identical to the sequence in the same direction (e.g. 5' to 3') on the complementary strand. This definition of palindrome thus depends on complementary strands being palindromic of ...
This resulting sequence is palindromic because it is the reverse complement of itself. [1] 5' TTACGCGTAA 3' test sequence (from Step 2 with intervening nucleotides removed) 3' AATGCGCATT 5' complement of test sequence 5' TTACGCGTAA 3' reverse complement This is the same as the test sequence above, and thus, it is a palindrome.
Many of them are palindromic, meaning the base sequence reads the same backwards and forwards. [29] In theory, there are two types of palindromic sequences that can be possible in DNA. The mirror-like palindrome is similar to those found in ordinary text, in which a sequence reads the same forward and backward on a single strand of DNA, as in ...
An asymmetric three allele STR locus that can be used to observe deletions and recombinational rearrangements in the palindromic region of the Y chromosome. 17-29 (many incomplete alleles) nomenclature: DYF401 DYF401 is a palindromic region marker. DYF406S1 11 DYF408 DYF408 is a palindromic region marker. DYF411 DYF411 is a palindromic region ...
In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand its features, function, structure, or evolution. It can be performed on the entire genome, transcriptome or proteome of an organism, and can also involve only selected segments or regions ...
A third study found more than 2,000 genes differentially methylated between colon cancers and adjacent mucosa. Using gene set enrichment analysis, 569 out of 938 gene sets were hypermethylated and 369 were hypomethylated in cancers. [28] Hypomethylation of CpG islands in promoters results in overexpression of the genes or gene sets affected.
This structure is thought to destabilize the binding of RNA polymerase enzyme to DNA (hence terminating transcription). Dyad symmetry is known to have a role in the rho independent method of transcription termination in E. coli. [citation needed] Regions of dyad symmetry in the DNA sequence stall the RNA polymerase enzyme as it transcribes them.
The consensus sequence of the E-box is usually CANNTG; however, there exist other E-boxes of similar sequences called noncanonical E-boxes. These include, but are not limited to: CACGTT sequence 20 bp upstream of the mouse Period2 gene and regulates its expression [13] CAGCTT sequence found within the MyoD core enhancer [14]