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The subcallosal cingulate gyrus CG25 which consists of BA25 as well as parts of BA24 and BA32 has been implicated as playing an important role in major depression and has been the target of deep brain stimulation to treat the disorder. [6] One study found that BA25 is metabolically overactive in treatment-resistant depression. [7]
The cingulate gyrus is heavily implicated in depressive disorders. The subgenual region, which lies below the genu of the corpus callosum, is especially important. [7] This site is the target of deep-brain stimulation therapy for depression, an invasive therapy used when all other treatment methods have failed. [7]
Electroconvulsive Therapy (ECT): ECT remains a cornerstone of interventional psychiatry, especially for severe, treatment-resistant depression and catatonia. The procedure involves controlled electrical currents to the brain, inducing a seizure that can lead to significant improvements in mood and behavior.
DBS has also been under investigational use for treatment resistant depression. Beginning in the 1950s, treatment has been attempted in the subcallosal cingulate region [52] and the ventral capsule/ventral striatum (VC/VS) [53] have shown mixed outcomes.
It is located beneath the cingulate gyrus within the medial surface of the brain therefore encircling the entire brain. There are two primary parts of the cingulate cortex: the posterior cingulate cortex and the anterior cingulate cortex. The anterior is linked to emotion, especially apathy and depression. Here function and structure changes ...
Getting rid of the penny, which cost the government 3 cents each, could end up costing the Treasury Department money if it has to make more nickels, which cost nearly 14 cents each to make and ...
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