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Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C 5 H 4 N 4 O 3.It forms ions and salts known as urates and acid urates, such as ammonium acid urate.
Struvite (magnesium ammonium phosphate) is a phosphate mineral with formula: NH 4 MgPO 4 ·6H 2 O. Struvite crystallizes in the orthorhombic system as white to yellowish or brownish-white pyramidal crystals or in platy mica-like forms. It is a soft mineral with Mohs hardness of 1.5 to 2 and has a low specific gravity of 1.7. It is sparingly ...
Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints. By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones.
Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [5]
Urate stones. Urate (C 5 H 4 N 4 O 3) stones, usually ammonium urate (NH 4 ·C 5 H 4 N 4 O 3) or sodium urate monohydrate (Na·C 5 H 4 N 4 O 3 ×H 2 O), form in an acidic to neutral urine. They are usually small, yellow-brown, smooth stones. Urate stones form due to an increased excretion of uric acid in the urine.
Crystals can be identified based on their appearance and the pH of the urine (many types preferentially form at an acidic or alkaline pH). [123] Crystals that can be found in normal urine include uric acid, monosodium urate, triple phosphate (ammonium magnesium phosphate), calcium oxalate, and calcium carbonate. [124]
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Crystallopathy is a harmful state or disease associated with the formation and aggregation of crystals in tissues or cavities, [1] [2] or in other words, a heterogeneous group of diseases caused by intrinsic or environmental microparticles or crystals, promoting tissue inflammation and scarring.