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Datopotamab deruxtecan, sold under the brand name Datroway, is an anti-cancer medication used for the treatment of breast cancer. [1] [2] It is a Trop-2-directed antibody and topoisomerase inhibitor antibody-drug conjugate.
144 302.22 g·mol −1 N Y (what is this?) (verify) Etaracizumab , also known as MEDI-522 , trade name Abegrin , is a humanized monoclonal antibody which is being investigated for the treatment of metastatic melanoma , prostate cancer , [ 1 ] ovarian cancer [ 2 ] and various other types of cancer. [ 3 ]
The fully human IgG2 monoclonal antibody glembatumumab (CR011) is linked to monomethyl auristatin E (MMAE). [citation needed] It uses a valine-citrulline enzyme-cleavable linker. [2] The linkage is stable in the bloodstream. The antibody binds to GPNMB on the cancer cells, the ADC is internalised, the linkage is broken and MMAE is released to ...
Resminostat (4SC-201 or RAS2410) is an orally bioavailable inhibitor of histone deacetylases (HDACs), of which inhibitors are antineoplastic agents. [1]In 2011, the German drug maker 4SC was granted orphan drug designation for resminostat by the US FDA for the treatment of hepatocellular carcinoma (HCC).
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Wolfgang Kaim (born 13 May 1951 in Bad Vilbel, Germany) is a German chemist who held the chair of coordination chemistry at the University of Stuttgart.He is co-author of the internationally recognized book, Bioinorganic Chemistry which was awarded with the Literature Award of the German Chemical Industry.
Buchanan Field Airport [2] (IATA: CCR, ICAO: KCCR, FAA LID: CCR) is a medium-sized general and business public airport in Contra Costa County, California, United States, [1] [3] one mile west of the center of Concord [1] [3] and just east of Pacheco in the San Francisco Bay Area. The airport's street address is 181 John Glenn Drive Ste. 100 ...