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A review article in U.S. Pharmacist in 2013 states that long-term use of PPIs is associated with decreased calcium absorption (causing increased risk of osteoporosis and fractures), decreased magnesium absorption (causing electrolyte disturbances), and increased risk of certain infections such as C. difficile and community-acquired pneumonia ...
Therefore, PPIs are often routinely prescribed for cirrhotic patients to treat GERD and prevent variceal bleeding. However, it has been recently shown that long term use of PPIs in patients with cirrhosis increases the risk of SBP and is associated with the development of clinical decompensation and liver-related death during long-term follow ...
When these medications are used long term, the lowest effective dose should be taken. [4] They may also be taken only when symptoms occur in those with frequent problems. [5] Proton-pump inhibitors are named using the suffix "-prazole". There is a purported correlation (but no proven causal link) between the use of PPIs and the risk of dementia ...
This study only followed participants for up to 2 years, so more research could examine the long-term effects. Future research can include randomized controlled trials and see if there are similar ...
The risk of liver injury is influenced by several factors including ... An enlarged liver is a rare side-effect of long-term steroid use in ... Omeprazole, Losartan, ...
The study found people with type 2 diabetes who are receiving treatment with GLP-1 and SGLT-2 medications have a lower risk of having COPD symptom flare-ups compared to those taking DPP-4 drugs ...
At the same time, the findings for clinical studies were more mixed, and long-term trials showed the possibility of a lower dementia risk with these drugs, but shorter trials did not show ...
At risk: No apparent necrotic bone in patients who have been treated with either oral or IV bisphosphonates No treatment indicated, Patient education N/A Stage 0: No clinical evidence of necrotic bone, but non-specific clinical findings, radiographic changes and symptoms Systemic management, including the use of pain medication and antibiotics N/A
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