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On average, exposures at 100 ppm or greater is dangerous to human health. [23] The WHO recommended levels of indoor CO exposure in 24 hours is 4 mg/m 3. [24] Acute exposure should not exceed 10 mg/m 3 in 8 hours, 35 mg/m 3 in one hour and 100 mg/m 3 in 15 minutes. [25]
This is increased in urban areas (7–13 ppm) and in smokers (20–40 ppm). [69] A carbon monoxide level of 40 ppm is equivalent to a reduction in hemoglobin levels of 10 g/L. [ 69 ] [ note 1 ] Carbon monoxide has a second toxic effect, namely removing the allosteric shift of the oxygen dissociation curve and shifting the foot of the curve to ...
Central chemoreceptors of the central nervous system, located on the ventrolateral medullary surface in the vicinity of the exit of the 9th and 10th cranial nerves, are sensitive to the pH of their environment. These act to detect the changes in pH of nearby cerebrospinal fluid (CSF) that are indicative of altered oxygen or carbon dioxide ...
Cerebral hypoxia is a form of hypoxia (reduced supply of oxygen), specifically involving the brain; when the brain is completely deprived of oxygen, it is called cerebral anoxia. There are four categories of cerebral hypoxia; they are, in order of increasing severity: diffuse cerebral hypoxia (DCH), focal cerebral ischemia, cerebral infarction ...
Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen (O. 2) at increased partial pressures. Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs, and eyes. Historically, the central nervous system condition was called the Paul Bert effect ...
Humans are the main indoor source of carbon dioxide (CO 2) in most buildings. Indoor CO 2 levels are an indicator of the adequacy of outdoor air ventilation relative to indoor occupant density and metabolic activity. Indoor CO 2 levels above 500 ppm can lead to higher blood pressure and heart rate, and increased peripheral blood circulation. [79]
Pulmonology, critical care medicine. Hypercapnia (from the Greek hyper = "above" or "too much" and kapnos = "smoke"), also known as hypercarbia and CO2 retention, is a condition of abnormally elevated carbon dioxide (CO 2) levels in the blood. Carbon dioxide is a gaseous product of the body's metabolism and is normally expelled through the lungs.
The brain is the central organ of the human nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sensory nervous system.