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  2. Substances poisonous to dogs - Wikipedia

    en.wikipedia.org/wiki/Substances_poisonous_to_dogs

    Zinc phosphide is a combination of phosphorus and zinc. If ingested, the acid in a dog's stomach turns the compound into phosphine, which is a toxic gas. The phosphine gas crosses into the dog's cells and causes the cell to die. Signs of poisoning include vomiting, anxiety, and loss of coordination.

  3. Grape toxicity in dogs - Wikipedia

    en.wikipedia.org/wiki/Grape_toxicity_in_dogs

    Canine dietary toxicity. The consumption of grapesand raisinspresents a potential health threat to dogs. Their toxicity to dogs can cause the animal to develop acute kidney injury(the sudden development of kidneyfailure) with anuria(a lack of urine production). The phenomenon was first identified by the Animal Poison Control Center (APCC), run ...

  4. Median lethal dose - Wikipedia

    en.wikipedia.org/wiki/Median_lethal_dose

    In toxicology, the median lethal dose, LD50 (abbreviation for " lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance. [ 1 ] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.

  5. Pentaerythritol tetranitrate - Wikipedia

    en.wikipedia.org/wiki/Pentaerythritol_tetranitrate

    Infobox references. Pentaerythritol tetranitrate (PETN), also known as PENT, pentyl, PENTA (ПЕНТА, primarily in Russian), TEN (tetraeritrit nitrate), corpent, or penthrite (or, rarely and primarily in German, as nitropenta), is an explosive material. It is the nitrate ester of pentaerythritol, and is structurally very similar to nitroglycerin.

  6. Nitenpyram - Wikipedia

    en.wikipedia.org/wiki/Nitenpyram

    Nitenpyram is a chemical frequently used as an insecticide in agriculture and veterinary medicine. The compound is an insect neurotoxin belonging to the class of neonicotinoids which works by blocking neural signaling of the central nervous system. It does so by binding irreversibly to the nicotinic acetylcholine receptor (nACHr) causing a stop ...

  7. Theobromine poisoning - Wikipedia

    en.wikipedia.org/wiki/Theobromine_poisoning

    The most common victims of theobromine poisoning are dogs, [8] [9] for whom it can be fatal. The toxic dose for cats is even lower than for dogs. [10] However, cats are less prone to eating chocolate since they are unable to taste sweetness. [11] Theobromine is less toxic to rats and mice, who all have an LD 50 of about 1,000 mg/kg (0.016 oz/lb).

  8. Afoxolaner - Wikipedia

    en.wikipedia.org/wiki/Afoxolaner

    Afoxolaner. Afoxolaner (INN [ 5 ]) is an insecticide and acaricide that belongs to the isoxazoline chemical compound group. It acts as an antagonist at GABA-receptors (those gated by the neurotransmitter gamma-aminobutyric acid) and other ligand-gated chloride channels.

  9. Aconitine - Wikipedia

    en.wikipedia.org/wiki/Aconitine

    Biologically active isolates from Aconitum and Delphinium plants are classified as norditerpenoid alkaloids, [ 1 ] which are further subdivided based on the presence or absence of the C18 carbon. [ 2 ] Aconitine is a C19-norditerpenoid, based on its presence of this C18 carbon. It is barely soluble in water, but very soluble in organic solvents ...