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101,100 (2015) [ 9 ] Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [ 6 ] Often, no symptoms are noticed initially. [ 10 ] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [ 10 ]
As the end stage of multiple myeloma that has failed or broken through one or more therapeutic regimens, sPCL continues to be highly refractory to various treatment regimens (<50%), very short response times of these regimens, and poor overall survival rates (median survival of 2–8 to months).
145461.60 g·mol −1. Elranatamab, sold under the brand name Elrexfio, is a medication used for the treatment of multiple myeloma. [ 8 ][ 12 ] Elranatamab is a bispecific B-cell maturation antigen (BCMA) -directed CD3 T-cell engager. [ 8 ][ 12 ][ 13 ][ 14 ] Elranatamab is given by subcutaneous injection. [ 8 ][ 12 ] The most common side ...
Treatment for multiple myeloma is focused on therapies that decrease the clonal plasma cell population and consequently decrease the signs and symptoms of disease. If the disease is completely asymptomatic (i.e. there is a paraprotein and an abnormal bone marrow population but no end-organ damage), as in smouldering myeloma, treatment is ...
Patti Scialfa is opening up for the first time about her six-year journey with multiple myeloma.. The longtime E Street Band member was diagnosed with the blood cancer in 2018, and has since faced ...
Some people can even end up getting a compression fracture of the spine while doing something as simple as carrying grocery bags, which would raise suspicion for multiple myeloma, Grajales-Cruz says.
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