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Amlexanox is the active ingredient in a common topical treatment for recurrent aphthous ulcers of the mouth (canker sores), [2] reducing both healing time [3] and pain. [4] Amlexanox 5% paste is well tolerated, [5] and is typically applied four times per day directly on the ulcers. [3] A 2011 review found it to be the most effective treatment ...
Buccal administration is a topical route of administration by which drugs held or applied in the buccal (/ ˈbʌkəl /) area (in the cheek) diffuse through the oral mucosa (tissues which line the mouth) and enter directly into the bloodstream. Buccal administration may provide better bioavailability of some drugs and a more rapid onset of ...
Diagramatic representation of mucosal erosion (left), excoriation (center), and ulceration (right) Simplistic representation of the life cycle of mouth ulcers. An ulcer (/ ˈ ʌ l s ər /; from Latin ulcus, "ulcer, sore") [2] is a break in the skin or mucous membrane with loss of surface tissue and the disintegration and necrosis of epithelial tissue. [3]
Frequency. ~30% of people to some degree [1] Deaths. None reported. Aphthous stomatitis, [2] or recurrent aphthous stomatitis (RAS), commonly referred to as a canker sore, is a common condition characterized by the repeated formation of benign and non- contagious mouth ulcers (aphthae) in otherwise healthy individuals.
Rebamipide, an amino acid derivative of 2- (1 H)-quinolinone, is used for mucosal protection, [1] healing of gastroduodenal ulcers, and treatment of gastritis. [2] It works by enhancing mucosal defense, scavenging free radicals, [3] and temporarily activating genes encoding cyclooxygenase-2. [4]
Sulfonated phenolics/sulfuric acid is used in the treatment of recurrent aphthous stomatitis (canker sores). Debacterol is available as a swab and in a liquid formulation. [citation needed] Sulfonated phenolics/sulfuric acid is not listed in the Physician's Desk Reference [2] and has not been approved by the Food and Drug Administration for any ...
Famotidine. Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4]
Sucralfate. Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. [ 3 ][ 4 ][ 5 ] Its usefulness in people infected by H. pylori is limited. [ 3 ]
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