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Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent ( dual antiplatelet therapy ). [ 10 ]
Management of acute coronary syndrome is targeted against the effects of reduced blood flow to the affected area of the heart muscle, usually because of a blood clot in one of the coronary arteries, the vessels that supply oxygenated blood to the myocardium. This is achieved with urgent hospitalization and medical therapy, including drugs that ...
Menopausal hormone therapy, clonidine, gabapentin, selective serotonin reuptake inhibitors [ 4 ][ 5 ] Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction. [ 1 ][ 6 ] It typically occurs between the ages of 45 and 55, although the exact timing can vary. [ 7 ]
As a result, the researchers concluded that people who are already taking a low-dose aspirin keep on taking it unless they have significant risk factors for aspirin-related bleeding.
For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset stomach. [10] More significant side effects include stomach ulcers, stomach bleeding, and worsening asthma. [10]
Mechanism of action of aspirin. Tridimensional model of the chemical structure of aspirin. Aspirin causes several different effects in the body, mainly the reduction of inflammation, analgesia (relief of pain), the prevention of clotting, and the reduction of fever. Much of this is believed to be due to decreased production of prostaglandins ...
CYP2C19. Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme protein. It is a member of the CYP2C subfamily of the cytochrome P450 mixed-function oxidase system. This subfamily includes enzymes that catalyze metabolism of xenobiotics, including some proton pump inhibitors and antiepileptic drugs. In humans, it is the CYP2C19 gene that ...
Non-steroidal anti-inflammatory drugs[ 1 ][ 3 ] (NSAID) [ 1 ] are members of a therapeutic drug class which reduces pain, [ 4 ] decreases inflammation, decreases fever, [ 1 ] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and ...
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