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Peeling skin syndrome in the legs and feet. Peeling skin syndrome (also known as acral peeling skin syndrome, continual peeling skin syndrome, familial continual skin peeling, idiopathic deciduous skin, and keratolysis exfoliativa congenita [1]) is an autosomal recessive disorder characterized by lifelong peeling of the stratum corneum, and may be associated with pruritus, short stature, and ...
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Keratolysis exfoliativa (also known as"lamellar dyshidrosis", [1] "recurrent focal palmar peeling", [2] "recurrent palmar peeling" [1]: 212 [2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet.
The dorsal surface of the toes, the heels, and the fingertips are other occasionally afflicted locations. The spared web gaps between the toes is a defining trait of juvenile plantar dermatosis. The symptoms of a lesion are bright, red, dry spots. Scaling and fissuring may be visible in chronic situations. [4]
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Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
The hands and feet usually are the first to show signs of the disease but the disease can advance to other parts of the body. Signs of the disease include thickening of the skin, on hands and soles of feet, which can turn red in color. [6] There currently is no cure and treatment is limited, but Acitretin can be used in severe cases. [7]
Ichthyosis (also named fish scale disease) [1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin. [2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive, autosomal or X-linked). [3]
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