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CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, [ 5 ] LFA-3 receptor, erythrocyte receptor and rosette receptor.
CD2 may refer to: CD2, (cluster of differentiation 2), a cell adhesion molecule; Chlordiazepoxide, by the trade name CD 2; CD-2, Color Developing Agent 2 - color film developer, used in photographic processing of Kodachrome film and ECP processes
23607 12488 Ensembl ENSG00000198087 ENSMUSG00000061665 UniProt Q9Y5K6 Q9JLQ0 RefSeq (mRNA) NM_012120 NM_009847 RefSeq (protein) NP_036252 NP_033977 Location (UCSC) Chr 6: 47.48 – 47.63 Mb Chr 17: 43.1 – 43.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. Function This gene encodes a scaffolding ...
The CD nomenclature was proposed and established in the 1st International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Paris in 1982. [4] [5] This system was intended for the classification of the many monoclonal antibodies (mAbs) generated by different laboratories around the world against epitopes on the surface molecules of leukocytes (white blood cells).
Complement receptor 2 interacts with CD19, [7] [8] and, on mature B cells, forms a complex with CD81 (TAPA-1). The CR2-CD19-CD81 complex is often called the B cell co-receptor complex, [9] because CR2 binds to opsonized antigens through attached C3d (or iC3b or C3dg) when the B-cell receptor binds antigen.
E-rosetting is used in the identification of T cells where a T cells CD2 surface protein is bound to a sugar based LFA-3 homologue on the surface of a sheep red blood cell. [1] Because the LFA-3 homologue is only present on the surface of sheep red blood cells other species red blood cells can not be used in this type of rosetting. [citation ...
CD58, lymphocyte-function antigen 3 (LFA-3), is a glycoprotein that plays a vital role in the body's immune response.The natural ligand to CD58, CD2, is most commonly found on the surfaces of both T cells and Natural Killer cells (T/NK cells). [3]
CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene. [5] [6] Interactions. CD2BP2 has been shown to interact with ...