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Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3] In 2022, it was the 149th most commonly prescribed medication in the United States, with more than 3 million prescriptions.
Chemically, it is a substituted phenethylamine and amphetamine and is closely related to phentermine and methamphetamine. [4] [9] [1] Mephentermine was first described and introduced for medical use by 1952. [10] It was discontinued in the United States between 2000 and 2004. [2] [7] The medication appears to remain available only in India.
Substituted amphetamines, or simply amphetamines, are a class of compounds based upon the amphetamine structure; [1] it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
A 2023 systematic review and meta-analysis looked into 14 trials of tirzepatide on more than 11,000 people with type 2 diabetes. It found that doses of 5 milligrams (mg), 10 milligrams and 15 ...
Promoting thicker hair and stronger nails. Boosting cardiovascular and gut health. ... Phentermine: Another appetite suppressant prescribed for short-term use only as it is an amphetamine ...
Phentermine-topiramate. This is a combination of an appetite suppressant called phentermine and an anticonvulsant called topiramate. Phentermine-topiramate is effective for weight loss and seems ...
Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
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