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Another class of medications known to occasionally cause itching is known as serotonin reuptake inhibitors. [3] Itching is one of the most frequent adverse effects of opioid therapy. [4] A common artificial colloid used in clinical fluid management is hydroxyethyl starch (HES).
One of the most prevalent forms of adverse drug reactions is cutaneous reactions, [1] with drug-induced urticaria ranking as the second most common type, preceded by drug-induced exanthems. [2] Urticaria, commonly known as hives , manifests as weals, itching, burning, redness, swelling, and angioedema —a rapid swelling of lower skin layers ...
DIHS is a delayed onset drug eruption, often occurring a few weeks to 3 months after initiation of a drug. [2] Worsening of systemic symptoms occurs 3–4 days after cessation of the offending drug. [5] There are genetic risk alleles that are predictive of the development of DIHS for particular drugs and ethnic populations. [5]
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Pruritis (itching) [4] Swelling [5] Induration (hardening of the skin) [6] Discoloration [6] Severe reactions may result in cutaneous necrosis at the injection site, typically presenting in one of two forms: (1) those associated with intravenous infusion or (2) those related to intramuscular injection.
Scientists are still unraveling the mystery of why skin conditions like eczema cause people to itch. One known cause is inflammation, which gets worse as people scratch and their skin becomes damaged.
Itching can also be caused by chronic kidney disease and related conditions. [2] Abirritants consist of a large group of drugs belonging to different classes with varying mechanisms to treat itch. They may work either directly or indirectly to relieve itch, and evidence on their effectiveness varies from one class to another. [3]
To diagnose a patient with functional itch disorder, the patient should meet three required criteria and three of seven optional criteria. [2] Diagnostic Criteria: [2] 3 Required criteria Localized or generalized pruritus without a primary skin lesion; Chronic pruritus, characterized as being greater than 6 weeks; There is no somatic cause present