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For example, the fourth generation of cephalosporins is not recognized as such in Japan. [citation needed] In Japan, cefaclor is classed as a first-generation cephalosporin, though in the United States it is a second-generation one; and cefbuperazone, cefminox, and cefotetan are classed as second-generation cephalosporins.
The basic structure of first generation cephalosporins. First generation cephalosporins were the first cephalosporins on the market. They have good antimicrobial activity against gram-positive bacteria but limited activity against gram-negative species. [25] The chemical structures of the first generation cephalosporins are fairly simple.
Cefazolin, also known as cefazoline and cephazolin, is a first-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [2] Specifically it is used to treat cellulitis, urinary tract infections, pneumonia, endocarditis, joint infection, and biliary tract infections. [2]
Cefalotin / ˌ s ɛ f ə ˈ l oʊ t ɪ n / or cephalothin / ˌ s ɛ f ə ˈ l oʊ θ ɪ n / is a first-generation cephalosporin antibiotic with broad spectrum antibiotic activity. [1] [2] It was the first cephalosporin marketed (1964) and continues to be widely used. [3]
Cefadroxil is a first-generation cephalosporin antibacterial drug that is the para-hydroxy derivative of cephalexin, and is used similarly in the treatment of mild to moderate susceptible infections such as the bacterium Streptococcus pyogenes, causing the disease popularly called strep throat or streptococcal tonsillitis, urinary tract infection, reproductive tract infection, and skin infections.
Cefalexin is a β-lactam antibiotic within the class of first-generation cephalosporins. [4] It works similarly to other agents within this class, including intravenous cefazolin, but can be taken by mouth. [5] Cefalexin can treat certain bacterial infections, including those of the middle ear, bone and joint, skin, and urinary tract. [4]
Cefalonium is a first-generation cephalosporin antibiotic. [1] References This page was last edited on 29 January 2023, at 20:33 (UTC). Text ...
Cefradine or cephradine is a first generation cephalosporin antibiotic. [1] Indications. Respiratory tract infections (such as ...