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Ketoconazole is a medication that treats a range of fungal infections. It belongs to a class of antifungal medications called imidazoles and works by slowing the growth of fungi that cause infection.
Topical antifungal drugs are used to treat fungal infections on the skin, scalp, nails, vagina or inside the mouth. These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus.
The side effects of ketoconazole are sometimes harnessed in the treatment of non-fungal conditions. While ketoconazole blocks the synthesis of the sterol ergosterol in fungi, in humans, at high dosages (>800 mg/day), it potently inhibits the activity of several enzymes necessary for the conversion of cholesterol to steroid hormones such as ...
Tinea cruris (TC), also known as jock itch, is a common type of contagious, superficial fungal infection of the groin and buttocks region, which occurs predominantly but not exclusively in men and in hot-humid climates. [3] [4] Typically, over the upper inner thighs, there is an intensely itchy red raised rash with a scaly well-defined curved ...
A 2015 review recommended topical antifungal agents, topical corticosteroids, and topical calcineurin inhibitors like tacrolimus as the main treatments for seborrheic dermatitis based on good-quality evidence, rather than selenium disulfide for which evidence is much more limited. [17]
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
Twelve of those patients were men who have sex with men. The American man’s infection responded to standard anti-fungal medications but ultimately took four and a half months to heal fully.
One of the studies included in the review found that of 18 people, 15 saw their toenail fungus at least partially clear up after dabbing the affected area with Vicks at least once a day for a year ...
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