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A false negative result may occur in a person who has been recently infected with TB, but whose immune system hasn't yet reacted to the bacteria. Upper respiratory virus infection In case a second tuberculin test is necessary it should be carried out in the other arm to avoid hypersensitising the skin.
The tine test is a multiple-puncture tuberculin skin test used to aid in the medical diagnosis of tuberculosis (TB). The tine test is similar to the Heaf test, although the Mantoux test is usually used instead. There are various forms of the tine tests which usually fall into two categories: the old tine test (OT) and the purified protein ...
Injecting a Mantoux skin test The Mantoux test for TB involves intradermally injecting PPD (Purified Protein Derivative) tuberculin and measuring the size of induration 48-72 hours later. The Mantoux skin test is used in the United States and is endorsed by the American Thoracic Society and Centers for Disease Control and Prevention .
The tuberculin skin test, commonly used for detection of other forms of tuberculosis, is not useful in the detection of miliary tuberculosis. The tuberculin skin test fails due to the high numbers of false negatives. [16] These false negatives may occur because of higher rates of tuberculin anergy compared to other forms of tuberculosis. [4]
A Mantoux tuberculin skin test. The Mantoux tuberculin skin test is often used to screen people at high risk for TB. [100] Those who have been previously immunized with the Bacille Calmette-Guerin vaccine may have a false-positive test result. [107] The test may be falsely negative in those with sarcoidosis, Hodgkin's lymphoma, malnutrition ...
The tuberculin skin test (TST) in its first iteration, the Mantoux Test, was developed in 1908. Tuberculin (also called purified protein derivative or PPD) is a standardised dead extract of cultured TB, injected into the skin to measure the person's immune response to the bacteria.
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Negative reaction to tuberculin skin test 2: TB infection No disease: Positive reaction to tuberculin skin test Negative bacteriologic studies (if done) No clinical, bacteriologic, or radiographic evidence of TB 3: TB, clinically active: M. tuberculosis cultured (if done) Clinical, bacteriologic, or radiographic evidence of current disease 4: TB