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Its purpose was to study epidemiology and control of malaria in the lowland rural Sudan savanna in northern Nigeria. [citation needed] The main objectives of the project were to measure the effects of indoor residual spraying and mass drug administration and to construct and test a mathematical model of malaria transmission. [1]
Mathematical models need to integrate the increasing volume of data being generated on host-pathogen interactions. Many theoretical studies of the population dynamics , structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem.
Plasmodium malariae is a parasitic protozoan that causes malaria in humans. It is one of several species of Plasmodium parasites that infect other organisms as pathogens, also including Plasmodium falciparum and Plasmodium vivax, responsible for most malarial infection.
Plasmodium knowlesi is a parasite that causes malaria in humans and other primates. It is found throughout Southeast Asia , and is the most common cause of human malaria in Malaysia . Like other Plasmodium species, P. knowlesi has a life cycle that requires infection of both a mosquito and a warm-blooded host.
Plasmodium is a eukaryote but with unusual features.. The genus Plasmodium consists of all eukaryotes in the phylum Apicomplexa that both undergo the asexual replication process of merogony inside host red blood cells and produce the crystalline pigment hemozoin as a byproduct of digesting host hemoglobin. [2]
Malaria is a mosquito-borne infectious disease that affects vertebrates and Anopheles mosquitoes. [6] [7] [3] Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. [1] [8] In severe cases, it can cause jaundice, seizures, coma, or death.
This approach is known as mathematical modeling and the above-mentioned physical parameters are called the model parameters or simply the model. To be precise, we introduce the notion of state of the physical system : it is the solution of the mathematical model's equation.
Plasmodium berghei is a single-celled parasite causing rodent malaria.It is in the Plasmodium subgenus Vinckeia.. Originally, isolated from thicket rats in Central Africa, P. berghei is one of four Plasmodium species that have been described in African murine rodents, the others being P. chabaudi, P. vinckei, and P. yoelii.