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Polyhydramnios is a medical condition describing an excess of amniotic fluid in the amniotic sac.It is seen in about 1% of pregnancies. [1] [2] [3] It is typically diagnosed when the amniotic fluid index (AFI) is greater than 24 cm. [4] [5] There are two clinical varieties of polyhydramnios: chronic polyhydramnios where excess amniotic fluid accumulates gradually, and acute polyhydramnios ...
It causes increased levels of amniotic fluid during pregnancy (polyhydramnios) and intestinal obstruction in newborn babies. Newborns present with bilious or non-bilous vomiting (depending on where in the duodenum the obstruction is) within the first 24 to 48 hours after birth, typically after their first oral feeding.
Oligohydramnios can sometimes be treated with bed rest, oral and intravenous hydration, antibiotics, steroids, and amnioinfusion. [citation needed] The opposite of oligohydramnios is polyhydramnios, an excess volume of amniotic fluid in the amniotic sac. Amniotic fluid embolism is a rare but very often fatal condition for both mother and child.
In maternal diabetes, 90% of pregnancy losses happen in the first trimester due to oxidative stress. Diabetic embryopathy abortions in the second-trimester are most likely due to severe birth defect , maternal metabolic derangement, placental insufficiency and fetal hypoxia due to membrane rupture.
Misoprostol can cause unpleasant side effects such as very high body temperatures and shivering. [27] Lower doses of misoprostol appear to be safer and cause less side effects. [27] Giving oxytocin in a solution of saline into the umbilical vein is a method of administering the drug directly to the placental bed and uterus. [28]
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Median AFI level is approximately 14 cm from week 20 to week 35, [6] when the amniotic fluid begins to reduce in preparation for birth. An AFI smaller than 5–6 cm is considered as oligohydramnios. [3] The exact number can vary by gestational age. The fifth percentile for gestational age is sometimes used as a cutoff value. [7]