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Common side effects include nausea, abdominal pain, and constipation. [2] It may worsen the symptoms of asthma. [2] Propranolol may cause harmful effects for the baby if taken during pregnancy; [7] however, its use during breastfeeding is generally considered to be safe. [8] It is a non-selective beta blocker which works by blocking β ...
Beta blockers vary in their lipophilicity (fat solubility) and in turn in their ability to cross the blood–brain barrier and exert effects in the central nervous system. [76] Beta blockers with greater blood–brain barrier permeability can have both neuropsychiatric therapeutic benefits and side effects, as well as adverse cognitive effects ...
Nicergoline is known to enhance the cardiac depressive effects of propranolol. [6] At high dosages, it is advisable to seek one's physician's guidance if combining with potent vasodilators such as bromocriptine , Ginkgo biloba , picamilon , vinpocetine or xantinol nicotinate .
[4] [28] Stress can affect children's growth and development, including the onset of puberty. [28] Some of the physical cues that may be indicative of stress in children are rashes on skin and skin diseases such as eczema , acne and hair loss , worsening asthma , insomnia or hypersomnia, frequent headaches, muscle aches, vomiting, constipation ...
Figure 1: The chemical structure of dichloroisoprenaline or dichloroisoproterenol (), abbreviated DCI — the first β-blocker to be developed. β adrenergic receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris but are now also used for hypertension, congestive heart failure and certain arrhythmias. [1]
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
This in turn may result in fewer effects in the central nervous system as well as a lower risk of neuropsychiatric side effects. [44] Only small amounts of atenolol are said to enter the brain. [ 2 ] [ 3 ] The brain-to-blood ratio of atenolol was 0.2 : 1 in one study, whereas the ratio for propranolol was 33 : 1 in the same study.
Anticholinergic side effects such as dry mouth and constipation are either greatly reduced in comparison to imipramine and most other TCAs or fully lacking with iprindole. [15] However, it still has significant antihistamine effects and therefore can produce sedation , though this is diminished relative to other TCAs similarly. [ 16 ]