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Drosophila melanogaster, commonly known as the fruit fly, has been a significant model organism in embryonic development research. Many of its genes that regulate embryonic development and their mechanisms of action have been crucial in understanding the fundamental principles of embryonic development regulation in many multicellular organisms ...
Drosophila embryogenesis, the process by which Drosophila (fruit fly) embryos form, is a favorite model system for genetics and developmental biology. The study of its embryogenesis unlocked the century-long puzzle of how development was controlled, creating the field of evolutionary developmental biology. [1]
Drosophila, usually the species Drosophila melanogaster – a kind of fruit fly, famous as the subject of genetics experiments by Thomas Hunt Morgan and others. Easily raised in lab, rapid generations, mutations easily induced, many observable mutations. Recently, Drosophila has been used for neuropharmacological research. [26]
[11] [12] Drosophila became one of the first, and for some time the most widely used, model organisms, [44] and Eric Kandel wrote that Morgan's discoveries "helped transform biology into an experimental science". [13] D. melanogaster remains one of the most widely used eukaryotic model organisms
Drosophila melanogaster is commonly used for animal experimentation. Most animal testing involves invertebrates, especially Drosophila melanogaster, a fruit fly, and Caenorhabditis elegans, a nematode. These animals offer scientists many advantages over vertebrates, including their short life cycle, simple anatomy and the ease with which large ...
The fruit fly Drosophila melanogaster made the jump from nature to laboratory animal in 1901. At Harvard University, Charles W. Woodworth suggested to William E. Castle that Drosophila might be used for genetical work. [3] Castle, along with his students, then first brought the fly into their labs for experimental use.
Gal4 is a modular protein consisting broadly of a DNA-binding domain and an activation domain. The UAS to which GAL4 binds is CGG-N 11-CCG, where N can be any base. [6] Although GAL4 is a yeast protein not normally present in other organisms it has been shown to work as a transcription activator in a variety of organisms such as Drosophila, [7] and human cells, highlighting that the same ...
One species of Drosophila in particular, Drosophila melanogaster, has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and " Drosophila " are often used synonymously with D. melanogaster in modern biological literature.