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In July 2024, the US Food and Drug Administration (FDA) approved Felanorm, the first generic methimazole oral solution for the treatment of hyperthyroidism in cats. [26] [27] [28] Felanorm contains the same active ingredient (methimazole) as the approved brand name drug product, Felimazole Coated Tablets, which were first approved in May 2009. [26]
Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T 3 and T 4 . It is on the World Health Organization's List of Essential Medicines.
Most are in the US. UC Davis have since abandoned their program. Kidney transplantation is a controversial treatment option, with longevity, quality of life, as well as ethical considerations. The United Kingdom permitted this procedure in 2003, but a review in 2013 suspended it. Many argue that it causes unnecessary suffering to donor animals. [2]
A systematic review from 2016 found that metamizole significantly increased the relative risk of upper gastrointestinal bleeding, by a factor of 1.4–2.7 times. [31] A study by one of the manufacturers of the drug found the risk of agranulocytosis within the first week of treatment to be a 1.1 in a million, versus 5.9 in a million for diclofenac.
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In December 2024, hardware modder Shank of the Shank Mods YouTube channel tracked down a functional PVM-4300, one of the last, in the second floor of a noodle restaurant in Osaka, Japan. [10] Shank, with the help of another person and a company involved in shipping of industrial equipment, arranged for the monitor to be shipped to the United ...
Monitor lizards are hunted, and their body fat, extracted by boiling, is used in a wide range of folk remedies. [33] Comparison to water monitor (Varanus salvator) In Sri Lanka, the Asian water monitor is considered venomous and dangerous when confronted, while the Bengal monitor (Thalagoya) is considered harmless and rather defenseless.
"Cool for Cats" is a song by English rock band Squeeze, released as the second single from their album of the same name. The song features a rare lead vocal performance from cockney-accented Squeeze lyricist Chris Difford , one of the only two occasions he sang lead on a Squeeze single A-side (the other was 1989's " Love Circles ").