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LINE1 (an abbreviation of Long interspersed nuclear element-1, also known as L1 and LINE-1) is a family of related class I transposable elements in the DNA of many groups of eukaryotes, including animals and plants, classified with the long interspersed nuclear elements (LINEs). [1]
Increased L1 copy numbers have also been found in the brains of people with schizophrenia, indicating that LINE elements may play a role in some neuronal diseases. [ 28 ] Mechanism of target-primed reverse transcription (TPRT) , directly at the site of integration: L1 RNP recognize AAAATT hexanucleotides and ORF2 endonuclease activity cleaves ...
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Line 6 is a musical instrument and audio equipment manufacturer, best known as a pioneer in guitar amplifier and effect modeling. [ 1 ] [ 2 ] The company's products include guitar effects , modeling guitar amplifiers , software , electric guitars , and wireless systems .
The L1s shared the boiler and many other components with the K4s 4-6-2 "Pacific" type, giving a total of 425 locomotives with many standard parts. [1]Although the L1s type was quite successful, it was very much eclipsed in PRR service by the larger and more powerful I1s/I1sa 2-10-0 "Decapods", which arrived in service only two years after the L1s and were very suited to the PRR's mountain ...
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