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The PICO process (or framework) is a mnemonic used in evidence-based practice (and specifically evidence-based medicine) to frame and answer a clinical or health care related question, [1] though it is also argued that PICO "can be used universally for every scientific endeavour in any discipline with all study designs". [2]
PICOT formatted questions address the patient population (P), issue of interest or intervention (I), comparison group (C), outcome (O), and time frame (T). Asking questions in this format assists in generating a search that produces the most relevant, quality information related to a topic, while also decreasing the amount of time needed to produce these search results.
A research question is "a question that a research project sets out to answer". [1] Choosing a research question is an essential element of both quantitative and qualitative research . Investigation will require data collection and analysis, and the methodology for this will vary widely.
A leading question is a question that suggests a particular answer and contains information the examiner is looking to have confirmed. [1] The use of leading questions in court to elicit testimony is restricted in order to reduce the ability of the examiner to direct or influence the evidence presented. Depending on the circumstances, leading ...
Evidence-based medicine (EBM) is a term that was first introduced by Gordon Guyatt. [10] Nevertheless, examples of EBM can be traced back to the early 1900s. Some contend that the earliest instance of EBM dates back to the 11th century when Ben Cao Tu Jing from the Song dynasty suggested a method to evaluate the efficacy of ginseng.
For example, Kai Huang wanted to determine what factors contributed to residential fires in U.S. cities. Three factors were posited to influence residential fires. These factors (environment, population, and building characteristics) became the hypotheses or conceptual framework he used to achieve his purpose – explain factors that influenced ...
In broad usage, the "practical clinical significance" answers the question, how effective is the intervention or treatment, or how much change does the treatment cause. In terms of testing clinical treatments, practical significance optimally yields quantified information about the importance of a finding, using metrics such as effect size, number needed to treat (NNT), and preventive fraction ...
Exploratory research is "the preliminary research to clarify the exact nature of the problem to be solved." It is used to ensure additional research is taken into consideration during an experiment as well as determining research priorities, collecting data and honing in on certain subjects which may be difficult to take note of without exploratory research.