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Although neurosyphilis is a neurological disease, neuropsychiatric symptoms might appear due to overall damage to the brain. These symptoms can make the diagnosis more difficult and can include symptoms of dementia , [ 9 ] [ 10 ] mania , psychosis , depression , [ 11 ] and delirium : [ 12 ] These symptoms are not always present, and when they ...
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...
Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases. [2] [3] Syphilis is most commonly spread through sexual activity. [2] It may also be transmitted from mother to baby during pregnancy or at birth, resulting in congenital syphilis.
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Treponema pallidum, formerly known as Spirochaeta pallida, is a microaerophilic, gram-negative, spirochaete bacterium with subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. [1] It is known to be transmitted only among humans and baboons. [2]
And importantly, diagnoses of primary and secondary syphilis — the most infectious stages of the infection — dropped 10% last year, to 53,000 cases. ... “That is huge cause for celebration ...
Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). [3]
Treatment cannot reverse any deformities, brain, or permanent tissue damage that has already occurred. [ 32 ] A Cochrane review found that antibiotics may be effective for serological cure but in general the evidence around the effectiveness of antibiotics for congenital syphilis is uncertain due to the poor methodological quality of the small ...