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55-year-old male with history of schizophrenia and long term chlorpromazine use. There is blue-gray dyspigmentation of the nose, bilateral cheeks, forearms, dorsal hands and arms in photo-distributed areas. Slit lamp examination shows diffuse punctate corneal deposits through the posterior stroma, descemet membrane, and endothelium of the cornea.
Submit a Suggestion. Stellate, anterior subcapsular cataract with granular, brown deposits along the suture lines in a patient taking chlorpromazine.
Title: Atlas Entry - Chlorpromazine-induced cataract Author: brettjohnson Created Date: 7/23/2019 12:18:26 PM
Title: Atlas Entry - Corneal and lenticular pi...tion from long-term chlorpromazine use Author: brettjohnson ...
This 52 year-old man has severe juvenile glaucoma. This eye has had multiple pan retinal photocoagulations. He has a blind eye that has has cyclophotocoagulation and retrobulbar chlorpromazine. The angle neovascularization grows up onto the cornea.
Dr. Ryan Diel is a Clinical Assistant Professor at University of Iowa Hospitals & Clinics. Dr. Diel completed his Ophthalmology Residency at the University of Iowa Department of Ophthalmology and Visual Sciences in June 2022.
Retinal toxicity (i.e. chloroquine, chlorpromazine) Unilateral somatic retinitis pigmentosa; X-linked retinitis pigmentosa carrier; Additional history was obtained and testing initiated to refine this differential. The patient had no history or evidence of trauma nor did she have a metallic intraocular foreign body.
Contributor: Jesse Vislisel, MD. Cornea verticillata, also known as vortex keratopathy, describes a pattern of whorl- shaped opacities within the basal corneal epithelium. They are most commonly located in the inferior paracentral region, are non-elevated, and can range from white to brown in color. These changes are usually not visually ...
On exam, she was noted to have granular lenticular opacities adjacent to the posterior capsule of the natural crystalline lens in the right eye. A diagnosis of posterior subcapsular cataract (PSC) was made. Factors such as diabetes mellitus, chlorpromazine use, or corticosteroids increase the risk of PSC formation. [1]
Supplementary Material Chapter 31. Case from Neovascular Glaucoma: 80-year-old man with recurrent vitreous hemorrhages, hyphema, and elevated intraocular pressure after a central retinal vein occlusion in the right eye.