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When the blood vessels suddenly relax, it results in vasodilation. In vasodilatory shock, the blood vessels are too relaxed leading to extreme vasodilation and blood pressure drops and blood flow becomes very low. Without enough blood pressure, blood and oxygen will not be pushed to reach the body's organs.
Distributive shock is a medical condition in which abnormal distribution of blood flow in the smallest blood vessels results in inadequate supply of blood to the body's tissues and organs. [ 1 ] [ 2 ] It is one of four categories of shock , a condition where there is not enough oxygen -carrying blood to meet the metabolic needs of the cells ...
If the degranulation is widespread, it can cause a shock-like syndrome similar to that of an allergic reaction. Anaphylatoxins indirectly mediate: smooth muscle cells contraction, for example bronchospasms; increase in the permeability of blood capillaries
Distributive shock is low blood pressure due to a dilation of blood vessels within the body. [6] [17] This can be caused by systemic infection (septic shock), a severe allergic reaction (anaphylaxis), or spinal cord injury (neurogenic shock). [citation needed
Septic shock is a subclass of distributive shock, a condition in which abnormal distribution of blood flow in the smallest blood vessels results in inadequate blood supply to the body tissues, resulting in ischemia and organ dysfunction. Septic shock refers specifically to distributive shock due to sepsis as a result of infection. [14]
It is usually the result of an infected heart valve, a central line-associated bloodstream infection (CLABSI), an infected blood clot (suppurative thrombophlebitis), or an infected blood vessel graft. [36] Persistent bacteremia can also occur as part of the infection process of typhoid fever, brucellosis, and bacterial meningitis. Left ...
The next step in treating end organ damage due to septic shock is to identify the source of the infection and treat it. Broad-spectrum antibiotics can be started that will treat many potential bacteria before cultures grow the specific bacteria that is causing the infection. Once cultures identify the culprit of the infection, the antibiotic ...
Anaphylactoid reaction, non-immune anaphylaxis, or pseudoanaphylaxis, is a type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation. [ 10 ] [ 42 ] Non-immune anaphylaxis is the current term, as of 2018, used by the World Allergy Organization [ 42 ] with some recommending that the old ...