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This stage is characterized by the presence of a minimum of 20% delta waves ranging from 0.5–2 Hz and having a peak-to-peak amplitude >75 μV. (EEG standards define delta waves to be from 0 to 4 Hz, but sleep standards in both the original R&K model ( Allan Rechtschaffen and Anthony Kales in the "R&K sleep scoring manual."), [ 63 ] [ 64 ] as ...
Sleep stages are characterized by spectral content of EEG: for instance, stage N1 refers to the transition of the brain from alpha waves (common in the awake state) to theta waves, whereas stage N3 (deep or slow-wave sleep) is characterized by the presence of delta waves. [107] The normal order of sleep stages is N1 → N2 → N3 → N2 → REM.
Slow-wave sleep (SWS), often referred to as deep sleep, is the third stage of non-rapid eye movement sleep (NREM), where electroencephalography activity is characterised by slow delta waves. [ 2 ] Slow-wave sleep usually lasts between 70 and 90 minutes, taking place during the first hours of the night. [ 3 ]
The activity of K-complexes is transferred to the thalamus where it synchronizes the thalamocortical network during sleep, producing sleep oscillations such as spindles and delta waves. [7] It has been observed that they are indeed identical in the "laminar distributions of transmembrane currents" to the slow waves of slow-wave sleep. [1]
A fictional EEG showing a sleep spindle and K-complex in stage 2 sleep.. Sleep spindles are bursts of neural oscillatory activity that are generated by interplay of the thalamic reticular nucleus (TRN) and other thalamic nuclei during stage 2 NREM sleep in a frequency range of ~11 to 16 Hz (usually 12–14 Hz) with a duration of 0.5 seconds or greater (usually 0.5–1.5 seconds).
Theta and delta waves are not generally seen in wakefulness - if they are, it is a sign of brain dysfunction. [ 3 ] EEG can detect abnormal electrical discharges such as sharp waves , spikes, or spike-and-wave complexes, as observable in people with epilepsy ; thus, it is often used to inform medical diagnosis .
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Tonic REM is characterized by theta rhythms in the brain; phasic REM is characterized by PGO waves and actual "rapid" eye movements. Processing of external stimuli is heavily inhibited during phasic REM, and recent evidence suggests that sleepers are more difficult to arouse from phasic REM than in slow-wave sleep.