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The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO − 3 ), and carbon dioxide (CO 2 ) in order to maintain pH in the blood and duodenum , among other tissues, to support proper metabolic function. [ 1 ]
Recall that the relationship represented in a Davenport diagram is a relationship between three variables: P CO 2, bicarbonate concentration and pH.Thus, Fig. 7 can be thought of as a topographical map—that is, a two-dimensional representation of a three-dimensional surface—where each isopleth indicates a different partial pressure or “altitude.”
An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acid–base imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [ 16 ] ).
Diagram of the circulatory system. SVC/IVC - Superior/Inferior vena cava. The heart is the driver of the circulatory system, pumping blood through rhythmic contraction and relaxation. The rate of blood flow out of the heart (often expressed in L/min) is known as the cardiac output (CO).
Solar System belts are asteroid and comet belts that orbit the Sun in the Solar System in interplanetary space. [1] [2] The Solar System belts' size and placement are mostly a result of the Solar System having four giant planets: Jupiter, Saturn, Uranus and Neptune far from the sun. The giant planets must be in the correct place, not too close ...
Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications. In nature, there are many living systems that use buffering for pH regulation. For example, the bicarbonate buffering system is used to regulate the pH of blood, and bicarbonate also acts as a buffer in the ocean.
The Kuiper belt is distinct from the hypothesized Oort cloud, which is believed to be a thousand times more distant and mostly spherical. The objects within the Kuiper belt, together with the members of the scattered disc and any potential Hills cloud or Oort cloud objects, are collectively referred to as trans-Neptunian objects (TNOs). [21]
Most importantly, the binding of carbon dioxide to hemoglobin helps buffer blood pH by preventing carbonic acid from decreasing the pH. [ 6 ] Although, the carbaminohemoglobin protein interacts with another protein (like hemoglobin) found in red blood cells, this interaction only takes place in the bloodstream and its products can be expelled.