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WormBase is an online biological database about the biology and genome of the nematode model organism Caenorhabditis elegans and contains information about other related nematodes. [1] [2] WormBase is used by the C. elegans research community both as an information resource and as a place to publish and distribute their results. The database is ...
Capitalizing on the World Wide Web, WormBook links in-text references (e.g. genes, alleles, proteins, literature citations) with primary biological databases such as WormBase and PubMed. C. elegans was the first multicellular organism to have its genome sequenced [6] and is a model organism for studying developmental genetics and neurobiology.
Anatomical diagram of a male C. elegans Video of C. elegans with pencil for scale There are 302 neurons in C. elegans, approximately one-third of all the somatic cells in the whole body. [ 22 ] Many neurons contain dendrites which extend from the cell to receive neurotransmitters or other signals, and a process that extends to the nerve ring ...
C. elegans has been used in studies of development and neurobiology. WormBase has information from nine species and five are from the genus Caenorhabditis, one of which is C. elegans. WormBase provides: a genome browser, genome, gene and protein sets for searches on sequence similarities and gene and protein summaries. [3]
C. nigoni is the closest relative of C. briggsae, and the two species can occasionally produce somewhat fertile hybrids. [12] Caenorhabditis remanei - genome sequenced by WashU GSC. [13] More closely related to C. briggsae than C. elegans, C. remanei is a gonochoristic (male-female obligate) species in the Elegans group.
C. elegans is amenable to transgenesis, the process of introducing foreign genetic material into the genome. [10] The most frequent method for generating transgenic worms is to inject exogenous DNA into the syncytial germ line; biolistic transformation can also be used. [10]
The doctors and nurses didn’t believe Tomisa Starr was having trouble breathing. Two years ago, Starr, 61, of Sacramento, California, was in the hospital for a spike in her blood pressure.
In its natural environment C. elegans is confronted with a variety of different potential pathogens. C. elegans has been used intensively as a model organism for studying host-pathogen interactions and the immune system. [5] [31] These studies revealed that C. elegans has well-functioning innate immune defenses.