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  2. Z-value (temperature) - Wikipedia

    en.wikipedia.org/wiki/Z-value_(temperature)

    "F 0" is defined as the number of equivalent minutes of steam sterilization at temperature 121.1 °C (250 °F) delivered to a container or unit of product calculated using a z-value of 10 °C. The term F-value or "F Tref/z " is defined as the equivalent number of minutes to a certain reference temperature (T ref ) for a certain control ...

  3. Sterilization (microbiology) - Wikipedia

    en.wikipedia.org/wiki/Sterilization_(microbiology)

    This method is a faster process than dry heat sterilization. Steam sterilization is performed using an autoclave, sometimes called a converter or steam sterilizer. The object or liquid is placed in the autoclave chamber, which is then sealed and heated using pressurized steam to a temperature set point for a defined period of time.

  4. List of instruments used in microbiological sterilization and ...

    en.wikipedia.org/wiki/List_of_instruments_used...

    Koch's or Arnold's steam sterilizer: used for steam sterilization A pressure cooker: used as a portable autoclave Biological and chemical indicators: Used to ascertain if a certain process has been completed, e.g. spores used in an autoclave are killed if autoclaving is properly done Filters: •Candle filter:

  5. List of ISO standards 10000–11999 - Wikipedia

    en.wikipedia.org/wiki/List_of_ISO_standards_10000...

    ISO 11737-2:2009 Part 2: Tests of sterility performed in the definition, validation and maintenance of a sterilization process ISO/IEC 11756:1999 Information technology - Programming languages - M ISO/TR 11766:2010 Intelligent transport systems – Communications access for land mobiles (CALM) – Security considerations for lawful interception

  6. Aseptic processing - Wikipedia

    en.wikipedia.org/wiki/Aseptic_processing

    Equipment used in aseptic processing of food and beverages must be sterilized before processing and remain sterile during processing. [1] When designing aseptic processing equipment there are six basic requirements to consider: the equipment must have the capability of being cleaned thoroughly, it must be able to be sterilized with steam, chemicals, or high-temperature water, sterilization ...

  7. Biological indicator evaluation resistometer - Wikipedia

    en.wikipedia.org/wiki/Biological_indicator...

    A BIER vessel evaluates the resistance of biological indicators to moist heat sterilization. [1] For example, if a 90% reduction is determined to be 5 minutes for the microorganism being evaluated, then a D-value of 5 is assigned. D values are specific to starting bioload, substrate (the material the spores are on), and microbe species.

  8. Autoclave - Wikipedia

    en.wikipedia.org/wiki/Autoclave

    A vacuum pump sucks air or air/steam mixtures from the chamber. Superatmospheric cycles: Achieved with a vacuum pump. It starts with a vacuum followed by a steam pulse followed by a vacuum followed by a steam pulse. The number of pulses depends on the particular autoclave and cycle chosen. Subatmospheric cycles:

  9. Process performance qualification protocol - Wikipedia

    en.wikipedia.org/wiki/Process_Performance...

    Process performance qualification protocol is a component of process validation: process qualification.This step is vital in maintaining ongoing production quality by recording and having available for review essential conditions, controls, testing, and expected manufacturing outcome of a production process.

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