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  2. Lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Lymphocytosis

    In adults, absolute lymphocytosis is present when the lymphocyte count is greater than 5000 per microliter (5.0 x 10 9 /L), in older children greater than 7000 per microliter and in infants greater than 9000 per microliter. [1] Lymphocytes normally represent 20% to 40% of circulating white blood cells. When the percentage of lymphocytes exceeds ...

  3. Hemophagocytic lymphohistiocytosis - Wikipedia

    en.wikipedia.org/wiki/Hemophagocytic_lymphohist...

    It is a life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of benign lymphocytes and macrophages that secrete high amounts of inflammatory cytokines. It is classified as one of the cytokine storm syndromes. There are inherited and non-inherited (acquired) causes of HLH.

  4. Lymphoproliferative disorders - Wikipedia

    en.wikipedia.org/wiki/Lymphoproliferative_disorders

    Lymphoproliferative disorders (LPDs) refer to a specific class of diagnoses, comprising a group of several conditions, in which lymphocytes are produced in excessive quantities. These disorders primarily present in patients who have a compromised immune system .

  5. Autoimmune lymphoproliferative syndrome - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_lymphoprolife...

    It is mostly well tolerated (though side effects include mucositis, diarrhea, hyperlipidemia, delayed wound healing) with drug-drug interactions. It has better activity against autoimmune disease and lymphoproliferation than mycophenolate mofetil and other drugs; however, sirolimus requires therapeutic drug monitoring and can cause mucositis.

  6. Monoclonal B-cell lymphocytosis - Wikipedia

    en.wikipedia.org/.../Monoclonal_B-cell_lymphocytosis

    Individuals with MBL usually present with unexplained increases in blood lymphocyte counts (i.e. lymphocytosis). The most common causes for lymphocytosis are viral infections, autoimmune diseases (particularly connective tissue diseases), hypersensitivity reactions, acute stress reactions, and prior splenectomy. [9]

  7. Epstein–Barr virus–associated lymphoproliferative diseases

    en.wikipedia.org/wiki/Epstein–Barr_virus...

    Epstein–Barr virus–associated lymphoproliferative diseases (also abbreviated EBV-associated lymphoproliferative diseases or EBV+ LPD) are a group of disorders in which one or more types of lymphoid cells (a type of white blood cell), i.e. B cells, T cells, NK cells, and histiocytic-dendritic cells, are infected with the Epstein–Barr virus (EBV).

  8. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    The experimental drug TGN1412—also known as Theralizumab—caused extremely serious symptoms when given to six participants in a Phase I trial. [2] A controlled and limited CRS is triggered by active fever therapy with mixed bacterial vaccines (MBV) according to Coley; it is used for oncological and certain chronic diseases. [19]

  9. Childhood leukemia - Wikipedia

    en.wikipedia.org/wiki/Childhood_Leukemia

    Most initial symptoms of leukemia are related to problems with the bone-marrow function. There are a variety of symptoms that children may experience. The symptoms tend to appear quickly in acute leukemia and slowly over time in chronic leukemia. [1] Symptoms in the different types of childhood leukemia include: feelings of fatigue or weakness

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