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  2. Hyperimmunoglobulin E syndrome - Wikipedia

    en.wikipedia.org/wiki/Hyperimmunoglobulin_E_syndrome

    An IgE level greater than 2,000 IU/mL is often considered diagnostic. [17] However, patients younger than 6 months of age may have very low to non-detectable IgE levels. Eosinophilia is also a common finding with greater than 90% of patients having eosinophil elevations greater than two standard deviations above the normal mean. [ 18 ]

  3. Immunoglobulin E - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_E

    IgE also plays a pivotal role in responses to allergens, such as anaphylactic reactions to drugs, bee stings, and antigen preparations used in desensitization immunotherapy. IgE is typically the least abundant isotype: blood serum IgE levels in a non-atopic individual are only 0.05% of the Ig concentration, [10] compared to 75% for the IgGs at

  4. Hypergammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Hypergammaglobulinemia

    Hypergammaglobulinemia is a condition that is characterized by the increased levels of a certain immunoglobulin in the blood serum. [1] The name of the disorder refers to an excess of proteins after serum protein electrophoresis (found in the gammaglobulin region). [citation needed]

  5. DOCK8 deficiency - Wikipedia

    en.wikipedia.org/wiki/DOCK8_deficiency

    DOCK8 deficiency, also called DOCK8 immunodeficiency syndrome, is the autosomal recessive form of hyperimmunoglobulin E syndrome, a genetic disorder characterized by elevated immunoglobulin E levels, eosinophilia, and recurrent infections with staphylococcus and viruses. It is caused by a mutation in the DOCK8 gene.

  6. Allergy - Wikipedia

    en.wikipedia.org/wiki/Allergy

    Quantitative IgE test results increase the possibility of ranking how different substances may affect symptoms. A rule of thumb is that the higher the IgE antibody value, the greater the likelihood of symptoms. Allergens found at low levels that today do not result in symptoms cannot help predict future symptom development.

  7. Allergic bronchopulmonary aspergillosis - Wikipedia

    en.wikipedia.org/wiki/Allergic_bronchopulmonary...

    Serum IgE can be used to guide treatment, and levels are checked every 6–8 weeks after steroid treatment commences, followed by every 8 weeks for one year. This allows for a determination of baseline IgE levels, though it's important to note that most patients do not entirely reduce IgE levels to baseline.

  8. Atopy - Wikipedia

    en.wikipedia.org/wiki/Atopy

    Atopy is the tendency to produce an exaggerated immunoglobulin E (IgE) immune response to otherwise harmless substances in the environment. [2] Allergic diseases are clinical manifestations of such inappropriate, atopic responses.

  9. Hypersensitivity - Wikipedia

    en.wikipedia.org/wiki/Hypersensitivity

    According to this system, known as the Gell and Coombs classification [6] or Gell-Coombs's classification, [7] there are four types of hypersensitivity, namely: type I, which is an Immunoglobulin E (IgE) mediated immediate reaction; type II, an antibody-mediated reaction mainly involving IgG or IgM; type III, an immune complex-mediated reaction ...

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