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Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [5] It is delivered subcutaneously either by injection or from an insulin pump. [5] [6] Onset of effects typically occurs within 30 minutes and lasts about 5 hours. [5]
A randomized, double blind trial published in JAMA in 1994 [5] showed that management for alcohol withdrawal that was guided by the CIWA scale resulted in decreased treatment duration and total use of benzodiazepines. The goal of the CIWA scale is to provide an efficient and objective means of assessing alcohol withdrawal.
These adverse effects are believed to be due to the neurotoxic effects of repeated withdrawal from alcohol on aberrant neuronal plasticity and cortical damage. Repeated periods of acute intoxication followed by acute detoxification has profound effects on the brain and is associated with an increased risk of seizures as well as cognitive deficits.
The rewarding effects of alcohol are attributed to dopamine, serotonin, GABA, endocannabinoids, serotonin and opioid peptides. [8] Alcohol is the most recreationally used drug internationally, [64] throughout history it has played a variety of roles, from medicine to a mood enhancer. Alcoholism and alcohol abuse however have undergone rigorous ...
It is possible in some cases that alcohol abuse via a kindling mechanism can cause the development of a chronic substance-induced psychotic disorder (e.g., schizophrenia). The effects of an alcohol-related psychosis include an increased risk of depression and suicide as well as psychosocial impairments. [2]
If you’re stuck on today’s Wordle answer, we’re here to help—but beware of spoilers for Wordle 1273 ahead. Let's start with a few hints.
A Canadian woman was arrested after trying to smuggle over 20 pounds of methamphetamine through a New Zealand airport, authorities said. The illicit drugs were disguised as Christmas presents, New ...
FORT PIERCE, Fla. — An "iron curtain" has descended here. Residents near a Cold War-era nuclear bomb shelter are wondering what the property's new owners are doing on the other side of the chain ...