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  2. Myelodysplastic syndrome - Wikipedia

    en.wikipedia.org/wiki/Myelodysplastic_syndrome

    The prognosis depends on the type of cells affected, the number of blasts in the bone marrow or blood, and the changes present in the chromosomes of the affected cells. [3] The average survival time following diagnosis is 2.5 years. [4] MDS was first recognized in the early 1900s; [5] it came to be called myelodysplastic syndrome in 1976. [5]

  3. International Prognostic Scoring System - Wikipedia

    en.wikipedia.org/wiki/International_Prognostic...

    The International Prognostic Scoring System (IPSS), originally published in 1997, is used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS). Based on the IPSS score, the patient's history, and the physician's own personal observations, the physician will design a treatment plan to address the MDS.

  4. Transfusion-dependent anemia - Wikipedia

    en.wikipedia.org/wiki/Transfusion-dependent_anemia

    As 70% of myelodysplastic syndrome patients exhibit transfusion dependent anemia, [17] diagnosis of MDS can also help indicate transfusion dependency. Diagnosis of it is complexed with great diversity of symptoms, [ 3 ] and therefore most patients are only diagnosed with myelodysplastic syndromes when seeking clinical advice after experiencing ...

  5. Chromosome 5q deletion syndrome - Wikipedia

    en.wikipedia.org/wiki/Chromosome_5q_deletion...

    This chromosome abnormality is most commonly associated with the myelodysplastic syndrome. It should not be confused with "partial trisomy 5q", though both conditions have been observed in the same family. [1] Diagnosis is achieved through marrow biopsy.

  6. Bone marrow failure - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow_failure

    Myelodysplastic syndrome (MDS) is a form of blood cancer in which the bone marrow no longer produces enough healthy, normal blood cells. [9] MDS are a frequently unrecognized and rare group of bone marrow failure disorders, yet the incidence rate has rose from 143 reported cases in 1973 to approximately 15,000 cases in the United States each year.

  7. Leukemia - Wikipedia

    en.wikipedia.org/wiki/Leukemia

    Clonal hematopoiesis is a common age-related phenomenon with a low risk of progression to myelodysplastic syndrome (MDS) and leukemia. [33] Once MDS has developed, the risk of progression to acute leukemia can be assessed using the International Prognostic Scoring System ( IPSS ).

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