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Luspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [ 5 ] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication .
A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. [3] Early on, no symptoms typically are seen. [3] Later, symptoms may include fatigue, shortness of breath, bleeding disorders, anemia, or frequent infections. [3]
Imetelstat, if approved, will be Geron's first commercial treatment in the market and will compete with Bristol Myers Squibb's Reblozyl, which received a label expansion by the FDA last year for ...
Geron is seeking approval of the injectable drug, called imetelstat, for treating transfusion-dependent anemia in patients with a group of blood cancers called myelodysplastic syndromes (MDS).
Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. [27] Autoimmune hemolytic anemia: D59.0-D59.1: Autoimmune hemolytic anemia (AIHA) is a type of hemolytic anemia where the body's immune system attacks its own red blood cells (RBCs), leading to their destruction .
Understanding what increases the risk of dementia can help doctors and policymakers identify people most at risk and provide the right support to slow down or lessen the impact of cognitive decline.
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There is currently no cure for MDS. The assessment of promyelocytes and their derivatives is an essential component of the diagnosis of various hematologic disorders. Laboratory test commonly used to evaluate promyelocyte abnormalities include complete blood count (CBC), morphologic evaluation of peripheral blood smears , flow cytometry , and ...
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