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  2. Methicillin-resistant Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Methicillin-resistant...

    Diagram depicting antibiotic resistance through alteration of the antibiotic's target site, modeled after MRSA's resistance to penicillin. Beta-lactam antibiotics permanently inactivate PBP enzymes, which are essential for cell wall synthesis and thus for bacterial life, by permanently binding to their active sites. Some forms of MRSA, however ...

  3. Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Staphylococcus_aureus

    Methicillin-resistant Staphylococcus aureus (MRSA, often pronounced / ˈ m ɜːr s ə / or / ɛ m ɑːr ɛ s eɪ /), is one of a number of greatly feared strains of S. aureus which have become resistant to most β-lactam antibiotics. For this reason, vancomycin, a glycopeptide antibiotic, is commonly used to combat MRSA. Vancomycin inhibits the ...

  4. ST8:USA300 - Wikipedia

    en.wikipedia.org/wiki/ST8:USA300

    ST8:USA300 is a strain of community-associated methicillin-resistant Staphylococcus aureus that has emerged as a particularly antibiotic resistant epidemic that is responsible for rapidly progressive, fatal diseases including necrotizing pneumonia, severe sepsis and necrotizing fasciitis. [1]

  5. Vancomycin-resistant Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Vancomycin-resistant...

    The diagnosis of vancomycin-resistant Staphylococcus aureus (VRSA) is performed by performing susceptibility testing on a single S. aureus isolate to vancomycin. This is accomplished by first assessing the isolate's minimum inhibitory concentration (MIC) using standard laboratory methods, including disc diffusion, gradient strip diffusion, and automated antimicrobial susceptibility testing ...

  6. Penicillin-binding proteins - Wikipedia

    en.wikipedia.org/wiki/Penicillin-binding_proteins

    Presence of the protein penicillin binding protein 2A (PBP2A) is responsible for the antibiotic resistance seen in methicillin-resistant Staphylococcus aureus (MRSA). [11] The β-lactam ring is a structure common to all β-lactam antibiotics. [12]

  7. Drug of last resort - Wikipedia

    en.wikipedia.org/wiki/Drug_of_last_resort

    One of the most commonly known examples of both antimicrobial resistance and the relationship to the classification of a drug of last resort is the emergence of Staphylococcus aureus (MRSA) (sometimes also referred to as multiple-drug resistant S. aureus due to resistance to non-penicillin antibiotics that some strains of S. aureus have shown ...

  8. MRSA ST398 - Wikipedia

    en.wikipedia.org/wiki/MRSA_ST398

    And Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that is resistant to many antibiotics. The abbreviation "ST" in MRSA ST398 refers to the sequence type of the bacterium. MRSA ST398 is a clonal complex 398 (CC398). This means that the strain had emerged in a human clinic, without any obvious or understandable causes.

  9. Staphylococcal infection - Wikipedia

    en.wikipedia.org/wiki/Staphylococcal_infection

    Methicillin-resistant Staphylococcus aureus (MRSA) – MRSA is one of the most common antibiotic-resistant strains of staph bacteria. It is more difficult to treat than other staph infections. MRSA causes rashes, boils, sores, and other abscesses.