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Serum level of 25(OH)D is the laboratory test ordered to indicate whether or not a person has vitamin D deficiency or insufficiency. [53] It is also considered reasonable to treat at-risk persons with vitamin D supplementation without checking the level of 25(OH)D in the serum, as vitamin D toxicity has only been rarely reported to occur. [53]
insufficient calcium absorption from the intestine because of lack of dietary calcium or a deficiency of, or resistance to, the action of vitamin D, or due to undiagnosed celiac disease. [ 18 ] phosphate deficiency caused by increased renal losses.
Causes of insufficient vitamin D synthesis in the skin include insufficient exposure to ultraviolet-B light from sunlight due to living in high latitudes (farther distance from the equator with resultant shorter daylight hours in winter). Serum concentration by the end of winter can be half that at the end of summer. [37]
Likewise, low vitamin D means lower calcium absorption. This double whammy can lead to a vicious cycle of dropping levels, putting us at risk for thin, weakened bones —and, ultimately ...
In a study by Mithal et al., [40] vitamin D insufficiency of various countries was measured by lower 25-hydroxyvitamin D. 25(OH) D is an indicator of vitamin D insufficiency that can be easily measured. These percentages should be regarded as relative vitamin D levels, and not as predicting evidence for development of rickets. [41]
The U.S. Preventive Services Task Force released a draft recommendation advising against using vitamin D to prevent falls and fractures in people over 60. Pharmacist Katy Dubinsky weighs in.
They also had a serum 25-hydroxy vitamin D level between 10 and 30 ng/mL, which indicates either “insufficient” vitamin D levels (below 30/mL) or vitamin D deficiency (below 20 ng/mL).
Vitamin D deficiency: Usually asymptomatic, causes reduce bone density (osteomalacia), rickets, myopathy, and is associated with the development of schizophrenia. It is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D (25(OH)D) in plasma, which is the most accurate measure of stores of vitamin D in the body ...
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