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Donald Wayne Seldin (October 24, 1920 – April 25, 2018) was an American nephrologist.He worked at University of Texas Southwestern Medical Center and served as chair of the department of medicine for 36 years.
The first step in urine formation is the filtration of blood in the kidneys. In a healthy human, the kidney receives between 12 and 30% of cardiac output, but it averages about 20% or about 1.25 L/min. The basic structural and functional unit of the kidney is the nephron.
Samuel Lee Kountz Jr. (October 30, 1930 – December 23, 1981) was an African-American kidney transplantation surgeon from Lexa, Arkansas.He was most distinguished for his pioneering work in the field of kidney transplantations, and in research, discoveries, and inventions in Renal Science.
The Glomerular filtration rate (GFR) is regarded as the best overall measure of the kidney's ability to carry out these numerous functions. An estimate of the GFR is used clinically to determine the degree of kidney impairment and to track the progression of the disease. The GFR, however, does not reveal the source of the kidney disease.
[citation needed] A large "staghorn" kidney stone may block all or part of the renal pelvis. The size of the renal pelvis plays a major role in the grading of hydronephrosis . Normally, the anteroposterior diameter of the renal pelvis is less than 4 mm in fetuses up to 32 weeks of gestational age and 7 mm afterwards. [ 2 ]
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).
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