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Verrucotoxin (VTX) is a lethal venom produced by the dorsal fins of Synanceia verrucosa. This species of reef stonefish is connected to the family Synanceiidae. The venom of this species of stonefish is a tetrameric glycoprotein with cardiovascular and cytolytic effects. [1]
Stonefish venom can be fatal at a dose of only 18 mg, which the fish is capable of releasing with only six of its thirteen spines. The protein makeup differs between the three species of stonefish, but in reef stonefish the fatal protein is the verrucotoxin protein. [15] Effects of the venom include severe pain, shock, paralysis, and tissue ...
Synanceiinae, or the family Synanceiidae, was first named and recognised as a grouping of related taxa by the English naturalist William John Swainson in 1839. [1] The 5th edition of Fishes of the World treats this grouping as a subfamily within the family Scorpaenidae, dividing the subfamily into the three tribes: Minoini, Choridactylini and Synanceiini. [3]
Synanceia is a genus of ray-finned fish belonging to the subfamily Synanceiinae, the stonefish, which is classified within the family Scorpaenidae, the scorpionfish and relatives. Stonefish are the most venomous fish known; stings can be fatal to humans. [2] [3] They are found in the coastal regions of the Indo-Pacific.
Synanceia nana, the Red Sea stonefish or dwarf scorpionfish, is a species of venomous, marine ray-finned fish, a stonefish belonging to the subfamily Synanceiinae which is classified as being within the family Scorpaenidae, the scorpionfishes and their relatives. It is found in the northwestern Indian Ocean.
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Little is known about the biological activity and composition of marine fish venoms, due to the difficulties in obtaining, storing and extracting venom samples.The National University of Singapore performed the first purification of the stonefish venom, because stonefish stings have been responsible for a number of deaths and severe poisoning cases in the local area. [1]
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