Search results
Results from the WOW.Com Content Network
One cup of grapefruit contains over 100% of your daily vitamin C, in addition to fiber, potassium, calcium, magnesium, and Vitamin B6, according to the U.S. Department of Agriculture.
Grapefruit contains vitamin C, a powerful antioxidant that can boost the immune system. Dietitians share health benefits and warning about medicine interaction.
This citrus fruit has loads of health benefits. But there are a few things to keep in mind before indulging.
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
Ciclosporin (cyclosporine, Neoral): Blood levels of ciclosporin are increased if taken with grapefruit juice, orange juice, or apple juice. [12] A plausible mechanism involves the combined inhibition of enteric CYP3A4 and MDR1, which potentially leads to serious adverse events (e.g., nephrotoxicity).
If a drug is not absorbed, then not enough of it is in the blood to have a therapeutic effect. Each affected drug has either a specific increase of effect or decrease. [24] One whole grapefruit or a glass of 200 ml (7 US fl oz) of grapefruit juice is enough to cause drug overdose toxicity. [21]
"There are certain substances in grapefruit juice and grapefruit that may affect the way the body handles a medication," says Leonard. "This can result in fluctuating levels of a medication in the ...
Naringenin is a flavanone from the flavonoid group of polyphenols. [2] It is commonly found in citrus fruits, especially as the predominant flavonone in grapefruit. [2]The fate and biological functions of naringenin in vivo are unknown, remaining under preliminary research, as of 2024. [2]