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Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. [2] [3] Along with an orally-administered gold salt, auranofin, it is one of only two gold compounds currently employed in modern medicine.
Salt is a mineral composed primarily of sodium chloride (NaCl) and is used in food for both preservation and flavor. Sodium ions are needed in small quantities by most living things, as are chlorine ions. Salt is involved in regulating the water content (fluid balance) of the body. Both sodium and chlorine ions are used for electrical signaling ...
An analysis of dietary guidelines found that this recommendation for restriction of salt intake is not supported by evidence from randomized controlled trials nor is it supported by evidence from prospective observational studies. The authors of this analysis suggest a redesign of the dietary guidelines for salt intake is needed. [36]
The guideline salt intake for adults is about 6 grams of salt (approximately one teaspoon). The Food Standards Agency estimate the average salt intake is about 8.6 grams/day [6] (2008). A high salt diet is likely to increase the risk of high blood pressure, which is associated with an increased risk of heart attack and stroke.
A low sodium diet has a useful effect to reduce blood pressure, both in people with hypertension and in people with normal blood pressure. [7] Taken together, a low salt diet (median of approximately 4.4 g/day – approx 1800 mg sodium) in hypertensive people resulted in a decrease in systolic blood pressure by 4.2 mmHg, and in diastolic blood pressure by 2.1 mmHg.
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For certain people with salt-sensitive blood pressure or diseases such as Ménière's disease, this extra intake may cause a negative effect on health. WHO guidelines [4] [5] state that adults should consume less than 2,000 mg of sodium/day (i.e. about 5 grams of traditional table salt), and at least 3,510 mg of potassium per day. [6]
Government regulatory agencies and clinical organizations, the European Food Safety Authority, the US Centers for Disease Control, and the American Heart Association recommend that consumers use less salt in their diets, mainly to reduce the risk of high blood pressure and associated cardiovascular diseases in adults and children.
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