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A softgel is an oral dosage form for medicine in the form of a specialized capsule. They consist of a shell, usually gelatin based, surrounding a liquid fill. Softgel shells are a combination of gelatin , water , opacifier and a plasticiser such as glycerin or sorbitol .
Gelatin capsules, informally called gel caps or gelcaps, are composed of gelatin manufactured from the collagen of animal skin or bone. [4] Vegetable capsules, introduced in 1989, [5] are made from cellulose, a structural component in plants. The main ingredient of vegetarian capsules is hydroxypropyl methyl cellulose. In the 21st century ...
Capsugel is a company that manufactures and sells two-piece hard gelatin drug capsules. [3]: 703 Capsugel also sells equipment for filling empty and liquid capsules, as well as equipment for sealing liquid capsules.
Gelatin is used as a binder in match heads [39] and sandpaper. [40] Cosmetics may contain a non-gelling variant of gelatin under the name hydrolyzed collagen (hydrolysate). Gelatin was first used as an external surface sizing for paper in 1337 and continued as a dominant sizing agent of all European papers through the mid-nineteenth century. [41]
In the 1800s, sugar coating and gelatin coating were invented, as were gelatin capsules. [1] In 1843, the British painter and inventor William Brockedon was granted a patent for a machine capable of "Shaping Pills, Lozenges, and Black Lead by Pressure in Dies". The device was capable of compressing powder into a tablet without the use of an ...
It is used primarily for gel capsules and as stabilizers for vaccines. [26] Non-animal derived alternatives to gelatin include pectin as a gelling agent or cellulose for creating capsules. [27] Lactose is derived from cow's milk and is a frequently used filler or binder in tablets and capsules. [28]
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