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William Bradley Coley (January 12, 1862 – April 16, 1936) was an American bone surgeon and cancer researcher best known for his early contributions to the study of cancer immunotherapy, specifically causing infection as a way to fight cancer, a practice used as far back as 1550 BC. [1]
Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies, while immunotherapies that reduce or suppress are classified as suppression immunotherapies .
William Coley (1862-1936), pioneer of cancer immunotherapy; Albert Coons (1912-1978), developed immunofluorescent techniques for labelling antibodies; Max D. Cooper (1933-), identification of T and B cells; Yehuda Danon (1940-) Deborah Doniach (1912-2004), organ-specific auto-immunity; Eva Engvall (1940-), one of the scientists who invented ...
Cancer immunotherapy (immuno-oncotherapy) is the stimulation of the immune system to treat cancer, improving the immune system's natural ability to fight the disease. [1] It is an application of the fundamental research of cancer immunology ( immuno-oncology ) and a growing subspecialty of oncology .
Immunotherapy for the treatment of cancer is an active area of medical research. [141] The main response of the immune system to tumors is to destroy the abnormal cells using killer T cells, sometimes with the assistance of helper T cells. [138] [142] Tumor antigens are presented on MHC class I molecules in a similar way to viral antigens.
The hospital was founded in its original building on the Upper West Side of Manhattan [2] in 1884 as New York Cancer Hospital by a group that included John Jacob Astor III and his wife Charlotte. [5] The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to eradicate tumors. [6]
The book, based on interviews with scientists and engineers who worked in Area 51, addresses the Roswell UFO incident [1] [2] and dismisses the alien story.. Instead, it suggests that Josef Mengele was recruited by the Soviet leader Joseph Stalin to produce "grotesque, child-size aviators" to be remotely piloted and landed in America to cause hysteria in the likeness of Orson Welles' 1938 ...
Allergen immunotherapy, also known as desensitization or hypo-sensitization, is a medical treatment for environmental allergies (such as insect bites) and asthma. [1] [2] Immunotherapy involves exposing people to larger and larger amounts of allergens in an attempt to change the immune system's response. [1]