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The prostate is the only male accessory gland that occurs in cetaceans, [66] consisting of diffuse urethral glands [67] surrounded by a very powerful compressor muscle. [68] The prostate gland originates with tissues in the urethral wall.
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [1] Symptoms may include frequent urination , trouble starting to urinate, weak stream, inability to urinate , or loss of bladder control . [ 1 ]
Prostate-specific antigen (PSA, also known as kallikrein III, seminin, semenogelase, γ-seminoprotein and P-30 antigen) is a 34-kD glycoprotein produced almost exclusively by the prostate gland. It is a serine protease (EC 3.4.21.77) enzyme, the gene of which is located on the 19th chromosome (19q13) in humans. [28]
Bulbourethral glands: located below the prostate near the base of the penis and secretes a clear, mucus like fluid which lubricates the urethra and neutralizes any acidic residue from urine. Its secretion, pre-ejaculate , may appear before ejaculation and serves to prepare the urethra for the safe passage of sperm.
The male accessory glands are the ampullary gland, seminal vesicle, prostate, bulbourethral gland, and urethral gland. [5]The products of these glands serve to nourish and activate the spermatozoa, to clear the urethral tract prior to ejaculation, serve as the vehicle of transport of the spermatozoa in the female tract, and to plug the female tract after placement of spermatozoa to help ensure ...
The glands may be the source of female ejaculation, [3] [4] [5] but this has not been proven. [4] Because they and the male prostate act similarly by secreting prostate-specific antigen (PSA), which is an ejaculate protein produced in males, and prostatic acid phosphatase, some authors refer to the Skene's glands as the "female prostate".
Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer.
Prostate cancer is typically found in men of ages older than 60 and its incidence increases with increasing age. NKX3-1 plays an essential role in normal murine prostate development. Loss of function of NKX3-1 leads to defects in prostatic protein secretions as well as ductal morphogenesis. Loss of function also contributes to prostate ...
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