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Sildenafil works well for most men with ED at any dosage, although the highest 100mg dosage produces improvements for a greater percentage of men than 50mg or 25mg. Sildenafil has an impressive ...
Sildenafil — does this by inhibiting an enzyme referred to as phosphodiesterase type 5, or PDE5. ... Even at the lowest prescribed dosage of 25mg, Viagra produced improvements in arousal for 63 ...
Like other prescription medicines, Viagra and its generic form, sildenafil, work best when you take them under the right conditions. Like other prescription medicines, Viagra and its generic form ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]
Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is to remedy ED. Other first-line treatment options for blood pressure and heart disease are ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.
Some authors recommend the use of sildenafil by mouth to replace the injectable drugs in cases of contraindications, although the efficacy of such medication is controversial. [ 45 ] Before the injection of the chosen drug, the flow pattern is monophasic, with low systolic velocities and an absence of diastolic flow.
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