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Medications that lower seizure threshold include the antidepressant and nicotinic antagonist bupropion, the atypical opioid analgesics tramadol and tapentadol, reserpine, [1] theophylline, [2] antibiotics (fluoroquinolones, imipenem, penicillins, cephalosporins, metronidazole, isoniazid) and volatile anesthetics. So can other factors, including:
Seizures are particularly notable due to tramadol's lowering of the seizure threshold, occurring in approximately half of acute poisoning cases. [43] Patients often exhibit tachycardia and mild hypertension. Gastrointestinal disturbances such as nausea and vomiting are common, and agitation, anxiety, and cold and clammy skin may also be present ...
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
Anticonvulsants suppress the excessive rapid firing of neurons during seizures. [6] Anticonvulsants also prevent the spread of the seizure within the brain. [7] Conventional antiepileptic drugs may block sodium channels or enhance γ-aminobutyric acid function. Several antiepileptic drugs have multiple or uncertain mechanisms of action. [8]
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
Indiana may not have been one of the very best teams in college football, but a team that goes 11-1 in a power conference was always going to be a foregone conclusion to make the 12-team College ...
The number of Americans filing new applications for unemployment benefits fell again last week, but many laid-off workers are experiencing long bouts of joblessness, keeping the door open to ...
France's government collapsed Wednesday after Prime Minister Michel Barnier was forced out in a no-confidence vote in Parliament, reigniting a summertime political crisis for the country as it ...